What are the benefits and risks of different treatments that could delay or slow the progression of progressive multiple sclerosis?

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What are the benefits and risks of different treatments that could delay or slow the progression of progressive multiple sclerosis? Key messages • Overall, we are very uncertain about the effects of treatments on relapses and slowing the worsening of disability. We did find evidence that rituximab after two years and interferon beta-1b after three years of treatment probably slightly reduce the number of people who experience relapses. • The number of people who stop taking a drug because of harmful events is slightly higher with interferon beta-1a, and probably slightly higher with...

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